Journal: Frontiers in Oncology
Article Title: Case report: Triple-negative breast cancer with low tumour-infiltrating lymphocytes infiltration and good prognosis: a case of Tall Cell Carcinoma with Reversed Polarity and review of the literature
doi: 10.3389/fonc.2024.1455893
Figure Lengend Snippet: Tumour TILs infiltration assessment, TILs were stained by haematoxylin and eosin (HE) staining, CD4 + T lymphocytes, CD8 + T lymphocytes were stained by immunohistochemical (IHC) staining. (A) TILs < 10% (×100). (B) A small number of interstitial CD4 + T lymphocytes infiltrated (×100). (C) Small amount of interstitial CD8 + T lymphocyte infiltration (×100). (D-F) Common triple-negative breast cancer control. (D) TILs > 40% (×100). (E) CD4 + positive expression (×100). (F) CD8 + positive expression (×100).
Article Snippet: In addition, there are no studies on TILs infiltration in the TME of TCCRP, and we compared the present case with a case of common TNBC according to the international guidelines on TILs detection published by the International Immuno-Oncology Biomarker Working Group in 2014 , with immunohistochemical detection of CD4 + T cell and CD8 + T cell expression to first explore the characteristics of TCCRP TILs infiltration.
Techniques: Staining, Immunohistochemical staining, Immunohistochemistry, Control, Expressing